Cadmium's alarming effects on Male Zebrafish revealed
Published: 05:12 PM,Dec 27,2023 | EDITED : 09:12 PM,Dec 27,2023
Mr. Maklas Al Marshoudi
MUSCAT: A study conducted by a research team led by Maklas bin Said al Marshoudi, lecturer, University of Technology and Applied Sciences, (UTAS) Muscat, is among the winning innovative research projects in the 10th National Research Award, organised by the Ministry of Higher Education, Research and Innovation.
The team won the prize in the Environmental and Biological Resources field under the Young Researcher’s category for ‘Additive effects of microplastics on accumulation and toxicity of cadmium in male zebrafish.’
The zebrafish (Danio rerio) is a freshwater fish belonging to the minnow family (Cyprinidae) of the order Cypriniformes. A popular aquarium fish, they are native to India and South Asia, and is frequently sold under the trade name zebra danio (and thus often called a ‘tropical fish’ although both tropical and subtropical).
Elaborating on his project, Maklas al Marshoudi says that microplastics (MPs) have emerged as contaminants of concern because of their ubiquitous presence in almost all aquatic environments. The ecological effects of MPs are complex and depend on multiple factors, including their age, size, and the ecological matrix. There is an urgent need for multi-factorial studies to elucidate their impacts.
Maklas explained that there was an additive interaction between water-borne cadmium (Cd) and MPs on bio-accumulation in males, but not in females. Cd accumulation increased by twofold when water-borne Cd and MPs were combined. Water-borne Cd-induced significantly higher levels of metallothionein compared to MPs pre-exposed to Cd. However, Cd-treated MPs caused greater damage to the intestine and liver compared to untreated MPs suggesting that bound Cd could be released or modulate MPs toxicity.
The research team also showed that co-exposure to water-borne Cd and MPs increased anxiety in the zebrafish, compared with water-borne Cd alone, suggesting using microplastics as a vector may increase toxicity. This study demonstrated that MPs could enhance the toxicity of Cd, but further study is needed to elucidate the mechanism.
According to Maklas, the most important finding of the research is the ability of microplastics to increase cadmium toxicity and accumulation in the studied fish. The toxicological interaction of microplastics and other conventional toxicants is still not fully understood and there is a global need for more research in this area.
The research project was published in Chemosphere. Other than Maklas, the research team also included Dr Hassan al Raisi, Dr Aziz al Habsi and Dr Michael J Barry.
Maklas stated that the national recognition is for 'years of hard work and dedication to environmental research. The award acknowledged the importance and the critical role that researchers play in the nation's development and prosperity.'
The team won the prize in the Environmental and Biological Resources field under the Young Researcher’s category for ‘Additive effects of microplastics on accumulation and toxicity of cadmium in male zebrafish.’
The zebrafish (Danio rerio) is a freshwater fish belonging to the minnow family (Cyprinidae) of the order Cypriniformes. A popular aquarium fish, they are native to India and South Asia, and is frequently sold under the trade name zebra danio (and thus often called a ‘tropical fish’ although both tropical and subtropical).
Elaborating on his project, Maklas al Marshoudi says that microplastics (MPs) have emerged as contaminants of concern because of their ubiquitous presence in almost all aquatic environments. The ecological effects of MPs are complex and depend on multiple factors, including their age, size, and the ecological matrix. There is an urgent need for multi-factorial studies to elucidate their impacts.
Maklas explained that there was an additive interaction between water-borne cadmium (Cd) and MPs on bio-accumulation in males, but not in females. Cd accumulation increased by twofold when water-borne Cd and MPs were combined. Water-borne Cd-induced significantly higher levels of metallothionein compared to MPs pre-exposed to Cd. However, Cd-treated MPs caused greater damage to the intestine and liver compared to untreated MPs suggesting that bound Cd could be released or modulate MPs toxicity.
The research team also showed that co-exposure to water-borne Cd and MPs increased anxiety in the zebrafish, compared with water-borne Cd alone, suggesting using microplastics as a vector may increase toxicity. This study demonstrated that MPs could enhance the toxicity of Cd, but further study is needed to elucidate the mechanism.
According to Maklas, the most important finding of the research is the ability of microplastics to increase cadmium toxicity and accumulation in the studied fish. The toxicological interaction of microplastics and other conventional toxicants is still not fully understood and there is a global need for more research in this area.
The research project was published in Chemosphere. Other than Maklas, the research team also included Dr Hassan al Raisi, Dr Aziz al Habsi and Dr Michael J Barry.
Maklas stated that the national recognition is for 'years of hard work and dedication to environmental research. The award acknowledged the importance and the critical role that researchers play in the nation's development and prosperity.'